Moisturisation Study

 

Moisturisers affect the appearance of skin by doing three things -- fighting dryness, balancing skin tone and improving skin texture. Moisturising products achieve these goals by helping the skin absorb water and by filling in the spaces between skin cells to replace lost moisture

Moisturisers can claim to make skin look younger, healthier, brighter and more even. They might promise to minimize pores or to firm, tighten and tone skin. Some even claim to fight wrinkles or reduce sun damage. We can help substantiate moisturising claims such as:

  • 24h Replenishing Moisturiser
  • Hydration
  • Moisturisation
  • Revitalise and nourish the skin

All of our Moisturisation studies are performed in environmentally controlled conditions – 45% humidity and 20°C, in a panel consisting of approximately 20 volunteers. They are performed for a specified time period e.g. 12h, 24h or 48h depending on the requirements of the Sponsor.

Typically, we would evaluate the moisturising potential of products (with an untreated control site) over the specified time period with instrumentation measurements taken at predetermined time points as follows:

  • A single-centre, within subject comparison study would be performed in a population of 20 female subjects with very dry skin. Recruited subjects will be asked to perform a wash-out phase 3 days prior to study commencement. They will be asked not to apply any moisturisers or use moisturising products on the legs during this wash-out phase.
  • Baseline (0h) Corneometer® measurements will be taken on sites demarcated on the lower legs. Test Material(s) will then be applied to the lower leg by test personnel. There will be one untreated control site. Subjects will have further Corneometer measurements taken at pre-determined assessment times (30 min, 2, 4, 6, 8, 10, 12h… etc.) post treatment.
  • The primary endpoints for analyses are the percentage change from pre-treatment to each of the post-treatment time points for Corneometer® measurements for each of the test materials. To calculate the percentage change for the Corneometer, the mean of the measurements at each time point will be used.

We can offer bespoke study design and protocols to support claims or match any specific marketing requirements.

Our expert team are here to discuss your specific needs, assist you with study method selection and guide you through the appropriate regulatory requirements.